Polyether_Polyether Polyol Knowledge DL-Pantoyl Lacyone DL-Pantoyl Lacyone

DL-Pantoyl Lacyone DL-Pantoyl Lacyone

DL-pantoyl lactone structural formula

Structural formula

Business number 01Q1
Molecular formula C6H10O3
Molecular weight 130.14
label

DL-2-hydroxy-3,3-dimethyl-4-butyrolactone,

DL-α-Hydroxy-β,β-dimethyl-γ-butyrolactone,

Dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone,

DL-Pantolactone

Numbering system

CAS number:79-50-5

MDL number:MFCD00064333

EINECS number:201-210-7

RTECS number:None

BRN number:80958

PubChem number:24879247

Physical property data

1. Characteristics: deliquescent columnar crystals.


2. Density (g/mL,25/4℃): Unsure


3. Relative vapor density (g/mL,AIR=1): Unsure


4. Melting point (ºC):80 ℃


5. Boiling point (ºC,Normal pressure):130℃ 2.4kPa)


6. Boiling point (ºC,5.2kPa): Unsure


7. Refractive index: Uncertain


8. Flash point (ºC): Unsure


9. Specific optical rotation (º): Unsure


10. Autoignition point or ignition temperature (ºC): Unsure


11. Vapor pressure (kPa,25ºC): Unsure


12.3. Isotonic specific volume (90.2K): 277.4


4. Surface Tension (dyne/cm):38.1


5. Polarizability10-24cm3):12.32

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): 0.5

2. Number of hydrogen bond donors: 1

3. Number of hydrogen bond acceptors: 3

4. Number of rotatable chemical bonds: 0

5. Number of tautomers: 3

6. Topological molecule polar surface area 46.5

7. Number of heavy atoms: 9

8. Surface charge: 0

9. Complexity: 139

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 0

12. Uncertain number of atomic stereocenters: 1

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

None yet

Storage method

This product should be sealed and stored in a cool place.

Synthesis method

Produced from isobutyraldehyde2,2-Dimethyl-3-After adding hydroxypropionaldehyde with sodium cyanide, it is obtained by hydrolysis, acidification and lactonization. 2,2- Dimethyl-3- Dissolve hydroxypropionaldehyde in water, put it into the reaction pot, and then add sodium cyanide aqueous solution and calcium chloride aqueous solution. Stir well and add 50% sulfuric acid solution. The reaction produces highly toxic hydrogen cyanide tail gas, which is absorbed by ferrous sulfate solution. At60-65℃ Reaction6hAfter that, heat up To80-85℃ Reaction3h, reduce stress Concentrate, add 95%95% -SIZE: 9pt; FONT-FAMILY: 宋体; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial; mso-font-kerning: 0pt; mso-bidi-font-family: Arial”> Ethanol precipitates inorganic salts. Filtration, the filtrate is decompressed to recover ethanol and then fractionated to collect130-145 ℃1.33-2.44 kPa) fraction, get DL-Panthenolactone.

Purpose

This product is an intermediate of pantothenic acid and is also used in other organic synthesis.

Arial; mso-font-kerning: 0pt”>-3-Hydroxypropionaldehyde is added with sodium cyanide, and then hydrolyzed, acidified, and lactonized to obtain it.2,2-Dimethyl -3-hydroxypropyl Dissolve the aldehyde in water, put it into the reaction pot, then add sodium cyanide aqueous solution and calcium chloride aqueous solution. Stir evenly and add 50%sulfuric acid solution. The reaction produces highly toxic hydrogen cyanide tail gas, which is absorbed by ferrous sulfate solution. At60-65℃ Reaction6hAfter that, heat up To80-85℃ Reaction3h, reduce stress Concentrate, add 95%95% -SIZE: 9pt; FONT-FAMILY: 宋体; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial; mso-font-kerning: 0pt; mso-bidi-font-family: Arial”> Ethanol precipitates inorganic salts. Filtration, the filtrate is decompressed to recover ethanol and then fractionated to collect130-145 ℃1.33-2.44 kPa) fraction, get DL-Panthenolactone.

Purpose

This product is an intermediate of pantothenic acid and is also used in other organic synthesis.

This article is from the Internet, does not represent the position of Toluene diisocyanate reproduced please specify the source.https://www.polyether-factory.com/archives/14267

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