Polyether_Polyether Polyol Knowledge Scopolamine Hydrobromide Scopolamine Hydrobromide

Scopolamine Hydrobromide Scopolamine Hydrobromide

Structural formula of scopolamine hydrobromide

Structural formula

Business number 037B
Molecular formula C17H22BrNO4
Molecular weight 384.26
label

Scopolamine hydrobromide,

Hyoscyamine hydrobromide,

Scopolamine bromide,

Hyoscine hydrobromide,

Hyoscine hydrochloride,

Anesthetic,

aromatic compounds

Numbering system

CAS number:114-49-8

MDL number:MFCD00012647

EINECS number:204-050-6

RTECS number:YM4550000

BRN number:None

PubChem ID:None

Physical property data

1. Characteristics: White orthorhombic crystals , Odorless and bitter.


2. Density (g/mL, 25): Undetermined


3. Relative vapor density (g/mL,Air =1): Undetermined


4. Melting point (ºC):195


5. Boiling point (ºC,normal pressure): Undetermined


6. Boiling point (ºC,KPa)Undetermined


7. Refractive Index n20/D):Undetermined


8. Flashpoint (ºC): Undetermined


9. Specific rotation (ºC): Undetermined


10. Autoignition point or ignition temperature (ºC): Undetermined


11. Vapor pressure (mmHg,38ºC): Undetermined


12. Saturated vapor pressure (kPa, ºC): Undetermined


13. Heat of combustion (KJ/mol): Undetermined


14. Critical temperature (ºC): Undetermined


15. Critical pressure (KPa): Undetermined


Complexity:418


10. Number of isotope atoms:0


11. Determine the number of atomic stereocenters:5


12. Uncertain number of atomic stereocenters:0


13. Determine the number of stereocenters of chemical bonds:0


14. Uncertain number of chemical bond stereocenters:0


15. Number of covalent bond units: 2


Properties and stability

None yet

Storage method

Store in a sealed, dry, and away from light.

Synthesis method

Scopolamine is extracted from Amaranthus japonica as raw material. China’s traditional Chinese medicine anesthetic preparation, Yangjinhua, originated from the Mafei Powder of Huatuo, a famous doctor in the 2nd century AD. Its active ingredient is scopolamine. Use the goldenrod powder with 50Ethanol was percolated until the exudate was almost free of alkaloids. The leachate is distilled under reduced pressure to recover ethanol. The obtained extract is extracted with sulfuric acid. The extract is adjusted to pH9-10 by adding sodium carbonate, and extracted with chloroform. The extract is distilled to recover the chloroform to obtain total biomass. alkali, and then separate and form a salt to obtain this product. The total yield is 0.15%.

Purpose

Anticholinergics. Scopolamine is an alkaloid with the strongest pharmacological effect in scopolamine. It can be used to block parasympathetic nerves and can also be used as a central nervous system preparation. It acts like belladonna, but is stronger and shorter-lived. It can be used for anesthesia, analgesia, cough and asthma, and is effective for motion sickness. It can also be used to control stiffness and tremor in Parkinson’s disease.
Biochemical research.

The active ingredient of Huatu’s Mafei Powder is scopolamine. Use the goldenrod powder with 50Ethanol was percolated until the exudate was almost free of alkaloids. The leachate is distilled under reduced pressure to recover ethanol. The obtained extract is extracted with sulfuric acid. The extract is adjusted to pH9-10 by adding sodium carbonate, and extracted with chloroform. The extract is distilled to recover the chloroform to obtain total biomass. alkali, and then separate and form a salt to obtain this product. The total yield is 0.15%.

Purpose

Anticholinergics. Scopolamine is an alkaloid with the strongest pharmacological effect in scopolamine. It can be used to block parasympathetic nerves and can also be used as a central nervous system preparation. It acts like belladonna, but is stronger and shorter-lived. It can be used for anesthesia, analgesia, cough and asthma, and is effective for motion sickness. It can also be used to control stiffness and tremor in Parkinson’s disease.
Biochemical research.

This article is from the Internet, does not represent the position of Toluene diisocyanate reproduced please specify the source.https://www.polyether-factory.com/archives/17335

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