Hydroxypropyl cellulose has a wide range of applications and good development space

Hydroxypropyl cellulose, abbreviated as HPC in English, has a molecular formula of C36H70O19. It is a non-ionic cellulose ether with a white, off-white or grayish powder appearance. It is odorless and flammable. At room temperature, hydroxypropyl cellulose is soluble in water, soluble in methanol, ethanol, isopropyl alcohol, acetone, chloroform and other organic solvents, and insoluble in benzene, ether, etc. According to the different hydroxypropyl content, hydroxypropyl cellulose can be divided into two categories: highly substituted hydroxypropyl cellulose and low substituted hydroxypropyl cellulose.

The preparation methods of hydroxypropyl cellulose include: using cellulose and chlorinated propylene as materials and reacting; using cellulose and alkali as materials and reacting; using wood pulp and high-concentration sodium hydroxide as materials, After impregnation, an alkaline cellulose solution is generated, which is then filtered and reacted with propylene oxide. In comparison, due to the high molar substitution degree, the production of highly substituted hydroxypropyl cellulose is more difficult. Hydroxypropyl cellulose can be widely used in scientific research, chemical industry, medicine and other fields.

Highly substituted hydroxypropyl cellulose (H-HPC) is dispersible in water. The surface activity of the aqueous solution is moderate. It can swell in water to form a transparent to milky white viscous colloidal solution. It is soluble in a variety of organic solvents and has thermoplasticity and anti-biodegradability. . H-HPC can be used as a binder, thickener, film-forming agent, stabilizer, dispersant, etc., and is used in industry (such as coatings, inks, ceramics, batteries, etc.), food, pharmaceuticals, cosmetics and other industries. Since H-HPC exhibits liquid crystal properties at high concentrations, it can be used to prepare nanocellulose for chiral photons.

Low-substituted hydroxypropyl cellulose (L-HPC) can be used as tablet excipients in the pharmaceutical industry. It is mainly used as a tablet disintegrant. Due to its large surface area, high porosity and excellent water absorption properties, it is beneficial to Tablet molding can improve tablet disintegration performance at the same time, and has better compatibility with raw materials and excipients than other disintegrants. It can be used in the production of oxytetracycline tablets, erythromycin tablets and other drugs. In my country and large usage worldwide. In addition, L-HPC can also be used in adhesives and other fields.

According to the “Hydroxypropyl Cellulose Industry In-depth Market Research and Investment Strategy Suggestions Report 2021-2025” released by the Industrial Research Center , in overseas markets, the main manufacturers of hydroxypropyl cellulose include Hercules of the United States, Ashland Group of the United States, ShinEtsu of Japan, Nippon Soda of Japan, etc.; in my country In the market, the main manufacturers of hydroxypropyl cellulose include Huzhou Zhanzhan Pharmaceutical, Anhui Shanhe Pharmaceutical Excipients, Shandong Liaocheng Ahua Pharmaceutical, Taian Ruitai Cellulose, etc.

Industry analysts said that hydroxypropyl cellulose can be used as a binder, thickener, film-forming agent, and stabilizer , dispersants, tablet disintegrants, etc., are widely used in industry, medicine, food, cosmetics, scientific research and other fields. Among them, L-HPC is an important tablet disintegrant with a large demand in the pharmaceutical field; H-HPC can be used in a wider range of applications and can even be used to prepare nanocellulose for chiral photons. Overall, there is good room for development of hydroxypropylcellulose.