Aminoglutethimide DL-Aminogluthamide

Structural formula

Business number	03JU
Molecular formula	C13H16N2O2
Molecular weight	232.28
label	triamperidone, Trifenadone, fenacetate, aminoglumide, 3-ethyl-3-(4-aminophenyl)-2,6-piperidinedione, Phenylethyl piperidone, DL-Aminoglutethimide, inhibitors, inhibitor

• Numbering system
• Physical property data
• Toxicological data
• Ecological data
• Molecular structure data
• Computing chemical data
• More
  • Properties and Stability
  • Storage method
  • Synthesis method
  • Purpose

Numbering system

CAS number:125-84-4

MDL number:None

EINECS number:None

RTECS number:None

BRN number:None

PubChem ID:None

Physical property data

1. Character: white crystal, bitter taste

2. Solubility: Hardly soluble in water, easily soluble in organic solvents

Toxicological data

None

Ecological data

None

Molecular structure data

5. Molecular property data:

1. Molar refractive index: 64.58

2. MooreVolume (m³/mol): 197.9

3. isotonic specific volume (90.2K):517.4

4. Surface Tension (dyne/cm):46.6

5. Polarizability（10^-24cm³):32.41

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP):6

2. Number of hydrogen bond donors: 4

3. Number of hydrogen bond acceptors: 6

4. Number of rotatable chemical bonds: 17

5. Number of tautomers: 4

6. Topological molecular polar surface area (TPSA):132

7. Number of heavy atoms: 34

8. Surface charge: 0

9. Complexity: 684

3. Number of hydrogen bond acceptors: 6

4. Number of rotatable chemical bonds: 17

5. Number of tautomers: 4

6. Topological molecular polar surface area (TPSA):132

7. Number of heavy atoms: 34

8. Surface charge: 0

9. Complexity: 684

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 0

12. The number of uncertain atomic stereocenters: 4

13. Determine the number of stereocenters of chemical bonds: 0

14. Uncertain number of chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

Basic properties: It inhibits the cleavage enzyme system that converts cholesterol into pregnenolone.

Storage method

Storage: Store at room temperature.

Synthesis method

Brief description of production method: It is prepared from 2-p-chlorophenylbutanamide as raw material.

Purpose

Purpose: It is an adrenocortical hormone inhibitor and anti-cancer drug. Also used in hypercortisolism and advanced breast cancer after menopause or oophorectomy

y: 宋体”>10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 0

12. The number of uncertain atomic stereocenters: 4

13. Determine the number of stereocenters of chemical bonds: 0

14. Uncertain number of chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

Basic properties: It inhibits the cleavage enzyme system that converts cholesterol into pregnenolone.

Storage method

Storage: Store at room temperature.

Synthesis method

Brief description of production method: It is prepared from 2-p-chlorophenylbutanamide as raw material.

Purpose

Purpose: It is an adrenocortical hormone inhibitor and anti-cancer drug. Also used in hypercortisolism and advanced breast cancer after menopause or oophorectomy