2-Chloropyridine 2-Chloropyridine

Structural formula

Business number	02YP
Molecular formula	C5H4ClN
Molecular weight	113.54
label	2-Chloropyridine 99﹪, 2-Chloro-pyridin, o-Chloropyridine, α-Chloropyridine, 2clpy, Alpha-Chloropyridine, Pyridine, 2-chloro-, 2-Chloropyridine,99%

• Numbering system
• Physical property data
• Toxicological data
• Ecological data
• Molecular structure data
• Computing chemical data
• More
  • Properties and Stability
  • Storage method
  • Synthesis method
  • Purpose

Numbering system

CAS number:109-09-1

MDL number:MFCD00006228

EINECS number:203-646-3

RTECS number:US5950000

BRN number:105788

PubChem number:24855927

Physical property data

1. Characteristics: Colorless liquid.

2. Density (g/mL,25℃） ：1.2

3 . Relative vapor density (g/mL,air =1) : Undetermined

4. Melting point (ºC): -46

5. Boiling point (ºC,normal pressure): 168

6. Boiling point (ºC, 95.18kPa)：166

7. Refractive index (_D²⁰)：1.532

8. Flashpoint (ºC):65

9. Specific optical rotation (ºC): Undetermined

10. Autoignition point or ignition temperature (ºC):Undetermined

11. Vapor pressure (mmHg, 20ºC): 1.7

12. Saturated vapor pressure (kPa, 55 ℃)1.60

13. Heat of combustion (KJ/mol): Undetermined

14. Critical temperature (ºC): Undetermined

2, Mutagenicity

Microbial Salmonella Typhimurium mutation: 5mg/plate;

Sex chromosome loss and non-disjunction test in yeast cells: 4000ppm

Mouse lymphocyte mutation: 1920mg/L;

Mouse lymphocyte gene mutation: 400mg/L;

Cytogenetic analysis of mouse lymphocytes: 1980mg/L;

Ecological data

This substance is slightly harmful to water.

Molecular structure data

None

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): None

2. Number of hydrogen bond donors: 0

3. Number of hydrogen bond acceptors: 1

4. Number of rotatable chemical bonds: 0

5. Number of tautomers: none

6. Topological molecule polar surface area 12.9

7. Number of heavy atoms: 7

8. Surface charge: 0

9. Complexity: 56

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 0

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

Avoid contact with strong oxidants and acids.

Storage method

Stored in a cool, ventilated warehouse. Keep away from fire and heat sources. They should be stored separately from oxidants, acids, and food chemicals, and avoid mixed storage. Equipped with the appropriate variety and quantity of fire equipment. The storage area should be equipped with emergency release equipment and suitable containment materials.

Synthesis method

It is prepared by Sandmann reaction using 2-aminopyridine.

Purpose

Intermediates of antifungal agents such as pyrithione.

Protective equipment. The storage area should be equipped with emergency release equipment and suitable containment materials.

Synthesis method

It is prepared by Sandmann reaction using 2-aminopyridine.

Purpose

Intermediates of antifungal agents such as pyrithione.