guanine nucleoside

Structural formula

Business number	039H
Molecular formula	C10H13N5O5
Molecular weight	283.24
label	9-(β-D-Ribofuranosyl)guanine, Guanine-9-β-D-ribofuranoside, Heterocyclic compounds

• Numbering system
• Physical property data
• Toxicological data
• Ecological data
• Molecular structure data
• Computing chemical data
• More
  • Properties and Stability
  • Storage method
  • Synthesis method
  • Purpose

Numbering system

CAS number:118-00-3

MDL number:MFCD00010182

EINECS number:204-227-8

RTECS number:MF8750000

BRN number:625911

PubChem number:24895268

Physical property data

1. Characteristics: White or off-white crystallinitypowder

2. Density (g/mL,20℃） : Undetermined

3. Relative vapor density (g/mL,Air=1): Undetermined

4. Melting point (ºC): 250

5. Boiling point (ºC,normal pressure): Undetermined

6. Boiling point (ºC, KPa): Undetermined

7. Refractive index: Undetermined

8. Flashpoint (ºC): Undetermined

9. Specific optical rotation (º): -62

10. Autoignition point or ignition temperature (ºC): Undetermined

11. Vapor pressure (mmHg, ºC): Undetermined

12. Saturated vapor pressure (kPa, ºC): Undetermined

13. Heat of combustion (KJ/mol): Undetermined

14. Critical temperature (ºC): Undetermined

15. Critical pressure (KPa): Undetermined

16. Oil and water (octanol/Log value of the partition coefficient for water: undetermined

17. Explosion limit (%,V/V): Undetermined

18. Lower explosion limit ( %,V/V): Undetermined

19. Solubility:Slightly soluble in water, insoluble in ethanol, ether, soluble in acetic acid.

Toxicological data

1. Acute toxicity:Mouse abdominal cavityLD50：500mg/kg

Mouse veinLD50：180mg/kg

2. Reproductive toxicity: intraperitoneally administered to female mice after fertilization TDLO: 1g/kg, Lasts 13 days

Female fertilized mice intraperitoneally TDLO: 750mg/kg , lasting 13 days

Female fertilized mice intraperitoneally TDLO: 750mg/kg , lasting 10 days

3. Mutagenic: E. coli phage Inhibitory power: 1g/L

Human cell mutations: 1mmol/L

Ecological data

Slightly harmful to water.

Molecular structure data

None

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): None

2. Number of hydrogen bond donors: 5

3. Number of hydrogen bond acceptors: 6

4. Number of rotatable chemical bonds: 2

5. Number of tautomers: 9

6. Topological molecule polar surface area 155

7. Number of heavy atoms: 20

8. Surface charge: 0

9. Complexity: 446

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 4

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

Stable at normal temperature and pressure, avoid contact with strong oxidants and heat.

Storage method

Stored in a cool, ventilated warehouse. Keep away from fire and water sources. should be kept away from oxidizer, do not store together. Equipped with the appropriate variety and quantity of fire equipment. Suitable materials should be available in the storage area to contain spills.

Synthesis method

None

Purpose

Mainly used in the manufacture of acyclovir and trioxazole core The main raw materials of drugs such as glycosides and guanosine triphosphate sodium.

re”>3. Mutagenic: E. coli phage Inhibitory power: 1g/L

Human cell mutations: 1mmol/L

Ecological data

Slightly harmful to water.

Molecular structure data

None

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): None

2. Number of hydrogen bond donors: 5

3. Number of hydrogen bond acceptors: 6

4. Number of rotatable chemical bonds: 2

5. Number of tautomers: 9

6. Topological molecule polar surface area 155

7. Number of heavy atoms: 20

8. Surface charge: 0

9. Complexity: 446

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 4

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

Stable at normal temperature and pressure, avoid contact with strong oxidants and heat.

Storage method

Stored in a cool, ventilated warehouse. Keep away from fire and water sources. should be kept away from oxidizer, do not store together. Equipped with the appropriate variety and quantity of fire equipment. Suitable materials should be available in the storage area to contain spills.

Synthesis method

None

Purpose

Mainly used in the manufacture of acyclovir and trioxazole core The main raw materials of drugs such as glycosides and guanosine triphosphate sodium.